SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The `mpileup` command outputs DNA sequences that have been aligned against a known reference. On each output line it writes the reference position, optionally the reference DNA base at that position (obtained from a separate file) and all of the DNA bases that aligned to that position. As the output is ordered by position, reference data that is no longer needed is discarded once it has been printed out. Under certain conditions the data could be discarded too early, leading to an attempt to read from a pointer to freed memory. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. This bug is fixed in versions 1.21.1 and 1.22. There is no workaround for this issue.

The remote Fedora 44 host has a package installed that is affected by multiple vulnerabilities as referenced in the FEDORA-2026-28858c383e advisory.

    Update pysam

    Resolves CVE issues

Tenable has extracted the preceding description block directly from the Fedora security advisory.

Note that Nessus has not tested for these issues but has instead relied only on the application's self-reported version number.

The remote Fedora 44 host has packages installed that are affected by multiple vulnerabilities as referenced in the FEDORA-2026-cb321bebb5 advisory.

    Update to 1.23.1



Tenable has extracted the preceding description block directly from the Fedora security advisory.

Note that Nessus has not tested for these issues but has instead relied only on the application's self-reported version number.

The Linux/Unix host has one or more packages installed that are impacted by a vulnerability without a vendor supplied patch available.

  - SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The `mpileup`     command outputs DNA sequences that have been aligned against a known reference. On each output line it     writes the reference position, optionally the reference DNA base at that position (obtained from a     separate file) and all of the DNA bases that aligned to that position. As the output is ordered by     position, reference data that is no longer needed is discarded once it has been printed out. Under certain     conditions the data could be discarded too early, leading to an attempt to read from a pointer to freed     memory. This bug may allow information about program state to be leaked. It may also cause a program crash     through an attempt to access invalid memory. This bug is fixed in versions 1.21.1 and 1.22. There is no     workaround for this issue. (CVE-2026-31972)

Note that Nessus relies on the presence of the package as reported by the vendor.

ID	Name	Product	Family	Severity
315365	Fedora 44 : python-pysam (2026-28858c383e)	Nessus	Fedora Local Security Checks	high
304040	Fedora 44 : bcftools / htslib / samtools (2026-cb321bebb5)	Nessus	Fedora Local Security Checks	medium
303033	Linux Distros Unpatched Vulnerability : CVE-2026-31972	Nessus	Misc.	medium

Detections

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CVE-2026-31972

medium

Tenable Plugins

high

medium

medium