WireGuard, such as WireGuard 0.5.3 on Windows, does not fully account for the possibility that an adversary might be able to set a victim's system time to a future value, e.g., because unauthenticated NTP is used. This can lead to an outcome in which one static private key becomes permanently useless.
https://lists.zx2c4.com/pipermail/wireguard/2021-August/006916.html