Siemens SIMATIC S7-400 PN CPU devices with firmware 5.x allow remote attackers to cause a denial of service (defect-mode transition and service outage) via (1) malformed HTTP traffic or (2) malformed IP packets.
https://cert-portal.siemens.com/productcert/pdf/ssa-617264.pdf
http://www.us-cert.gov/control_systems/pdf/ICSA-12-212-02.pdf