Packeteer PacketShaper uses fixed increments in TCP initial sequence number (ISN) values, which allows remote attackers to predict the ISN value, and perform session hijacking or disruption.
http://www.vupen.com/english/advisories/2007/1891
http://www.securityfocus.com/bid/24048
http://www.securityfocus.com/archive/1/468972/100/0/threaded
http://securityreason.com/securityalert/2726