Trend OfficeScan Corporate Edition 5.58 and possibly earler does not drop privileges when opening a help window from a virus detection pop-up window, which allows local users to gain SYSTEM privileges.
https://exchange.xforce.ibmcloud.com/vulnerabilities/16375
http://www.securityfocus.com/bid/10503
http://uk.trendmicro-europe.com/enterprise/support/knowledge_base_detail.php?solutionId=20118
http://secunia.com/advisories/11806
http://archives.neohapsis.com/archives/bugtraq/2004-06/0117.html