McAfee VirusScan 4.5.1, when the WebScanX.exe module is enabled, searches for particular DLLs from the user's home directory, even when browsing the local hard drive, which allows local users to run arbitrary code via malicious versions of those DLLs.
https://exchange.xforce.ibmcloud.com/vulnerabilities/10741
http://www.securityfocus.com/bid/6288
http://archives.neohapsis.com/archives/bugtraq/2002-12/0007.html