Internet Explorer 5.x does not warn a user before opening a Microsoft Access database file that is referenced within ActiveX OBJECT tags in an HTML document, which could allow remote attackers to execute arbitrary commands, aka the "IE Script" vulnerability.
https://docs.microsoft.com/en-us/security-updates/securitybulletins/2000/ms00-049
http://www.securityfocus.com/templates/archive.pike?list=1&msg=39589359.762392DB%40nat.bg