Information
USB storage provides a means to transfer and store files ensuring persistence and availability of the files independent of network connection status. Its popularity and utility has led to USB-based malware being a simple and common means for network infiltration and a first step to establishing a persistent threat within a networked environment.
Restricting USB access on the system will decrease the physical attack surface for a device and diminish the possible vectors to introduce malware.
Solution
Run the following script to disable the usb-storage module:
-IF- the module is available in the running kernel:
 - Create a file ending inconf with install usb-storage /bin/false in the /etc/modprobe.d/ directory
 - Create a file ending inconf with blacklist usb-storage in the /etc/modprobe.d/ directory
 - Unload usb-storage from the kernel
-IF- available in ANY installed kernel:
 - Create a file ending inconf with blacklist usb-storage in the /etc/modprobe.d/ directory
-IF- the kernel module is not available on the system or pre-compiled into the kernel:
 - No remediation is necessary
#!/usr/bin/env bash
{
   l_mname="usb-storage" # set module name
   l_mtype="drivers" # set module type
   l_mpath="/lib/modules/**/kernel/$l_mtype"
   l_mpname="$(tr '-' '_' <<< "$l_mname")"
   l_mndir="$(tr '-' '/' <<< "$l_mname")"
   module_loadable_fix()
   {
      # If the module is currently loadable, add "install {MODULE_NAME} /bin/false" to a file in "/etc/modprobe.d"
      l_loadable="$(modprobe -n -v "$l_mname")"
      [ "$(wc -l <<< "$l_loadable")" -gt "1" ] && l_loadable="$(grep -P -- "(^h*install|b$l_mname)b" <<< "$l_loadable")"
      if ! grep -Pq -- '^h*install /bin/(true|false)' <<< "$l_loadable"; then
         echo -e "
 - setting module: \"$l_mname\" to be not loadable"
         echo -e "install $l_mname /bin/false" >> /etc/modprobe.d/"$l_mpname".conf
      fi
   }
   module_loaded_fix()
   {
      # If the module is currently loaded, unload the module
      if lsmod | grep "$l_mname" > /dev/null 2>&1; then
         echo -e "
 - unloading module \"$l_mname\""
         modprobe -r "$l_mname"
      fi
   }
   module_deny_fix()
   {
      # If the module isn't deny listed, denylist the module
      if ! modprobe --showconfig | grep -Pq -- "^h*blacklisth+$l_mpnameb"; then
         echo -e "
 - deny listing \"$l_mname\""
         echo -e "blacklist $l_mname" >> /etc/modprobe.d/"$l_mpname".conf
      fi
   }
   # Check if the module exists on the system
   for l_mdir in $l_mpath; do
      if [ -d "$l_mdir/$l_mndir" ] && [ -n "$(ls -A $l_mdir/$l_mndir)" ]; then
         echo -e "
 - module: \"$l_mname\" exists in \"$l_mdir\"
 - checking if disabled..."
         module_deny_fix
         if [ "$l_mdir" = "/lib/modules/$(uname -r)/kernel/$l_mtype" ]; then
            module_loadable_fix
            module_loaded_fix
         fi
      else
         echo -e "
 - module: \"$l_mname\" doesn't exist in \"$l_mdir\"
"
      fi
   done
   echo -e "
 - remediation of module: \"$l_mname\" complete
"
}
Impact:
Disabling the usb-storage module will disable any usage of USB storage devices.
If requirements and local site policy allow the use of such devices, other solutions should be configured accordingly instead. One example of a commonly used solution is USBGuard