Information
This policy setting controls whether database files (.dbf) opened from an untrusted location are always opened in Protected View.
Note: This policy setting only applies to subscription versions of Office, such as Microsoft 365 Apps for enterprise.
The recommended state for this setting is: Enabled
Files that originate from an untrusted location may contain malicious software. Requiring a user to open files originating from these zones forces them into a read-only mode. This reduces the chance of infection by making the user acknowledge a series of prompts before enabling editing.
Solution
To establish the recommended state via configuration profiles, set the following Settings Catalog path to Enabled
Microsoft Excel 2016\Excel Options\Security\Trust Center\Protected View\Always open untrusted database files in Protected View
Impact:
Database files opened from an untrusted location are always opened in Protected View. Users will not be able to change this setting under Trust Center Settings > Protected View.