Information
Virtualization-based Security (VBS) provides the platform for the additional security features, Credential Guard and virtualization-based protection of code integrity. Secure Boot is the minimum security level with DMA protection providing additional memory protection. DMA Protection requires a CPU that supports input/output memory management unit (IOMMU).
Solution
Virtualization-based security, including Credential Guard, currently cannot be implemented in virtual desktop implementations (VDI) due to specific supporting requirements including a TPM, UEFI with Secure Boot, and the capability to run the Hyper-V feature within the virtual desktop.
For VDIs where the virtual desktop instance is deleted or refreshed upon logoff, this is NA.
Configure the policy value for Computer Configuration >> Administrative Templates >> System >> Device Guard >> 'Turn On virtualization-based Security' to 'Enabled' with 'Secure Boot' or 'Secure Boot and DMA Protection' selected for 'Select Platform Security Level:'.
A Microsoft article on Credential Guard system requirement can be found at the following link.
https://technet.microsoft.com/en-us/itpro/windows/keep-secure/credential-guard-requirements